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We are proud of our open and transparent approach to scientific research, and we encourage you to explore our library and download our materials
 

Take a look at our peer-reviewed publications along with our posters, presentations and conference materials. Material published by Reynolds American Inc. from 2018 onwards can also be accessed through our library.

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Title:A scientific framework for assessing the risk profile of NGPs relative to smoking
Type:Poster
Author:McEwan, M.,Gale, N.,Eldridge, A.,Errington, G.,Graff, D.,Murphy, J.,Proctor, C.,Fearon, I.,Saraiva, A.
Description:ToxiLatin
Year:2018
Tags:Vype, Vapour, E-cig, E-cigarette, ePen, Glo, THP, Tobacco Heating Product, Heat-not-burn, Neostick, ToxiLatin
Title:A framework for assessing the reduced risk potential of e-cigarettes at individual and population levels
Type:Poster
Author:Murphy, J.,Fearon, I.,Camacho, O.,Gaca, M.,Prasad, K.,Kendall, B.,Proctor, C.
Description:Global Forum on Nicotine (GFN) Global Forum on Nicotine (GFN)
Year:2017
Tags:cardiovascular disease, CVD, lung cancer, chronic obstructive pulmonary disease, COPD, reduced risk, reduced exposure, assessment framework, pre-clinical, clinical, Population studies, emissions, in vitro, exposure, biomarkers of exposure, BoE, PMS, Post Market Surveillance, toxicants, vaping, vapour, e-cigarettes, e-cig, Global Forum on Nicotine (GFN)
Title:Genotoxicity evaluation of tobacco and nicotine delivery products: Part Two. In vitro micronucleus assay
Type:Publication
Author:Thorne, D.,Leverette, R.,Breheny, D.,Lloyd, M.,McEnaney, S.,Whitwell, J.,Clements, J.,Bombick, B.,Gaça, M.
Description:Food and Chemical Toxicology
Year:2019
Tags:In vitro, tobacco heating product, THP, E-cigarette, vaping, vapour, IVMN, TPM, E-liquid, Nicotine equivalents, Food and Chemical Toxicology,
Title:An inter-laboratory in vitro assessment of cigarettes and next generation nicotine delivery products
Type:Publication
Author:M. Taylor,S. Ilto,S. Mori,D. Thorne,T. Nishino ,D. Breheny,M. Gaca,K. Yoshino,C. Proctor
Year:2019
Tags:in vitro, vapour, e-cigarettes, tobacco heating products, THP, nicotine,
Title:Genotoxicity evaluation of tobacco and nicotine delivery products: Part One. Mouse lymphoma assay
Type:Publication
Author:Thorne, D.,Leverette, R.,Breheny, D.,Lloyd, M.,McEnaney, S.,Whitwell, J.,Clements, J.,Bombick, B.,Gaca, M.
Description:Food and Chemical Toxicology
Year:2019
Tags:In vitro, NGP, THP, tobacco heating products, E-cigarette, MLA, TPM, E-liquid, Nicotine equivalents, Mouse lymphoma assay, vaping, vapour, Food and Chemical Toxicology
Title:Extreme testing of undiluted e-cigarette aerosol in vitro using an Ames air-agar-interface technique
Type:Publication
Author:Thorne, D.,Hollings, M.,Seymour, A.,Adamson, J.,Dalrymple, A.,Ballantyne, M.,Gaca, M.
Description:Mutation Research
Year:2018
Tags:RTP, Reduced Toxicant Prototype, Mutation Research
Title:Characterisation of a vitrocell VC1 using nicotine dosimetry: An essential component toward standardised in vitro aerosol exposure of tobacco and next generation nicotine delivery products
Type:Publication
Author:Behrsing, H.,Aragon, M.,Adamson, J.,Sheehan, D.,Gaca, M.,Curren, R.,Hill, E.
Description:AIVT Volume 4, Number 2, 2018
Year:2018
Tags:THP, Tobacco Heating Product, Heat-not-burn, AIVT
Title:Studies support reduced risk potential of the Vype ePen e-cigarette
Type:Abstract
Author:Murphy, M.
Description:Studies support reduced risk potential of the Vype ePen e-cigarette
Year:2017
Tags:vaping, vapour, e-cigarettes, e-cig, vype, ePen, Studies support reduced risk potential of the Vype ePen e-cigarette
Title:The in vitro assessment of an e-cigarette (Vype ePen)
Type:Poster
Author:Adamson, J. ,Azzopardi, D. ,Breheny, D.,Crooks, I.,Hewitt, K.,Taylor, M.,Thorne, D.,Gaca, M.,Proctor, C.
Description:Society for Research on Nicotine and Tobacco (SRNT)
Year:2017
Tags:in vitro, pre-clinical, aerosol, toxicants, whole aerosol, WA, total particulate matter, TPM, Ames, cytotoxicity, oxidative stress, endothelial cells, vaping, vapour, e-cigarettes, e-cig, vype, ePen, Society for Research on Nicotine and Tobacco (SRNT)
Title:A novel approach for the screening of e-cigarette aerosols using an Ames whole aerosol assay
Type:Poster
Author:Thorne, D.,Hollings, M.,Seymour, A.,Crooks, I.,Meredith, C.,Gaca, M.
Description:Society of Toxicology (SOT)
Year:2017
Tags:aerosol, Ames, bacterial reverse mutation, mutagenicity, in vitro, WA, whole aerosol, TPM, total particulate matter, exposure, vaping, vapour, e-cigarettes, e-cig, Society of Toxicology (SOT)
Title:RNA-Seq based toxicogenomics comparison of airway cells exposed to Vype ePen vapour and cigarette smoke
Type:Presentation
Author:Minet, E.
Description:Sociedade Brasileira de Toxicologia (SBTOX)
Year:2017
Tags:vaping, vapour, e-cigarettes, e-cig, vype, ePen, in vitro, aerosol, airway, exposure chamber, exposure, RNA, tissue, sequence, toxicogenomics, COPD, chronic obstructive pulmonary disease, gene, Sociedade Brasileira de Toxicologia (SBTOX)
Title:The pre-clinic assessment of Vype ePen: A product for vaping
Type:Presentation
Author:Breheny, D.
Description:Sociedade Brasileira de Toxicologia (SBTOX)
Year:2017
Tags:in vitro, harm reduction, pre-clinical, air-liquid interface, exposure chamber, exposure systems, High content screening, mutagenicity, cytotoxicity, genotoxicity, WA, TPM, whole aerosol, total particulate matter, vaping, vapour, e-cigarettes, e-cig, vype, ePen, Sociedade Brasileira de Toxicologia (SBTOX)
Title:The comparative in vitro assessment of e-cigarette and cigarette smoke aerosols using the γH2AX assay and applied dose measurements
Type:Publication
Author:Thorne, D.,Larard, S.,Baxter, A.,Meredith, C.,Gaca, M.
Description:Toxicology Letters http://dx.doi.org/10.1016/j.toxlet.2016.12.006
Year:2017
Tags:vaping, vapour, e-cigarettes, e-cig, in vitro, genotoxicity, aerosols, high content screening, HCS, exposure systems, air-liquid interface, Toxicology Letters
Title:Nicotine quantification in vitro: A consistent dosimetry marker for e-cigarette aerosol and cigarette smoke generation
Type:Publication
Author:Adamson, J.,Li, X. ,Cui, H. ,Thorne, D.,Xie, F.,Gaca, M.
Description:Applied In Vitro Toxicology
Year:2017
Tags:vaping, vapour, e-cigarettes, e-cig, nicotine, in vitro, dosimetry, aerosol, air-liquid interface, puffing, regime, Applied In Vitro Toxicology
Title:Reduced biological effect of e-cigarette aerosol compared to cigarette smoke evaluated in vitro using normalized nicotine dose and RNA-seq-based toxicogenomics
Type:Publication
Author:Haswell, L.,Baxter, A.,Banerjee, A.,Verrastro, I.,Mushonganono, J.,Adamson, J.,Thorne, D.,Gaca, M.,Minet, E.
Description:Scientific Reports Scientific Reports
Year:2017
Tags:vaping, vapour, e-cigarettes, e-cig, in vitro, aerosol, airway, exposure chamber, exposure, RNA, tissue, sequence, toxicogenomics, COPD, chronic obstructive pulmonary disease, gene, Scientific Reports
Title:Vype ePen Chemistry RSC
Type:Poster
Author:McAdam, K.G.,Margham, J.,Wright, C.,Mariner, D.C.,Forster, M.,Liu, C.,Proctor, C.
Description:Royal Chemical Society (RSC)
Year:2016
Tags:aerosol, emissions, heated, toxicants, analytical chemistry, Harm reduction, HPHCs, Harmful and Potentially Harmful Constituents, vaping, vapour, e-cigarettes, e-cig, vype, ePen, Royal Chemical Society (RSC)
Title:The in vitro assessment of an electronic cigarette (Vype ePen) using a suite of pre-clinical tools
Type:Poster
Author:Gaca, M.,Breheny, D.,Crooks, I.,Lowe, F.,Taylor, M.,Minet, E.,Thorne, D.,Proctor, C.
Description:Global Forum on Nicotine (GFN)
Year:2016
Tags:in vitro, pre-clinical, aerosol, toxicants, whole aerosol, WA, total particulate matter, TPM, Ames, cytotoxicity, oxidative stress, endothelial cells, vaping, vapour, e-cigarettes, e-cig, vype, ePen, Global Forum on Nicotine (GFN)
Title:The mutagenic assessment of an electronic-cigarette and reference cigarette smoke using the Ames assay in strains TA98 and TA100
Type:Publication
Author:Thorne, D.,Crooks, I.,Hollings, M.,Seymour, A.,Meredith, C.,Gaca, M.
Description:Mutation Research/Genetic Toxicology and Environmental Mutagenesis
Year:2016
Tags:e-cigarette, e-cig, vaping, vapour, aerosol, Ames, bacterial reverse mutation, mutagenicity, in vitro, WA, whole aerosol, TPM, total particulate matter, exposure, Mutation Research/Genetic Toxicology and Environmental Mutagenesis
Title:E-cigarette Nicotine Delivery: Data and Learnings from Pharmacokinetic Studies
Type:Publication
Author:Fearon, I.,Eldridge, A.,Gale, N.,Shepperd, C. ,McEwan, M.,Camacho, O.,Nides, M.,McAdam, K.,Proctor, C.
Description:American Journal of Health Behavior
Year:2016
Tags:e-cigarette, e-cig, vaping, vapour, nicotine, PK, pharmacokinetic, pharmacokinetics, PK, PK profiles, kinetics, clinical, plasma nicotine concentrations, American Journal of Health Behavior
Title:Application of dosimetry tools for the assessment of e-cigarette aerosol and cigarette smoke generated on two different in vitro exposure systems
Type:Abstract
Description:Application of dosimetry tools for the assessment of e-cigarette aerosol and cigarette smoke generated on two different in vitro exposure systems
Year:2016
Tags:combustibles, cigarettes, e-cig, e-cigarette, vaping, vapour, Nicotine, dosimetry, in vitro, exposure systems, aerosol, exposure chamber, air-liquid interface, Application of dosimetry tools for the assessment of e-cigarette aerosol and cigarette smoke generated on two different in vitro exposure systems
Title:The genotoxicological assessment of a tobacco heating product relative to cigarette smoke using the in vitro micronucleus assay
Type:Publication
Author:David Thorne, James Whitwell, Julie Clements, Paul Walker, Damien Breheny, Marianna Gaca,
Description:The genotoxicological assessment of a tobacco heating product relative to cigarette smoke using the in vitro micronucleus assay Toxicology Reports
Year:2020
Tags:genotoxicological assessment, tobacco heating product, THP, glo, heat not burn, cigarette smoke, in vitro, micronucleus assay,
Title:Changes in Biomarkers of Exposure on Switching From a Conventional Cigarette to the glo Tobacco Heating Product: A Randomized, Controlled Ambulatory Study
Type:Publication
Author:Nathan Gale, Michael McEwan, Oscar M. Camacho, George Hardie, James Murphy, Christopher J Proctor,
Description:Changes in Biomarkers of Exposure on Switching From a Conventional Cigarette to the glo Tobacco Heating Product: A Randomized, Controlled Ambulatory Study Nicotine and Tobacco Research
Year:2020
Tags:Biomarkers of Exposure, glo, Tobacco Heating Product, THP, Ambulatory Study, BoE, toxicants, clinical study, glo 12 month clinical study,
Title:Evaluation of a high-throughput in vitro endothelial cell migration assay for the assessment of nicotine and tobacco delivery products
Type:Publication
Author:Emma Bishop, Damien Breheny, Katherine Hewitt, Mark Taylor, Tomasz Jaunky, Oscar M. Camacho, David Thorne, Marianna Gaca,
Description:Evaluation of a high-throughput in vitro endothelial cell migration assay for the assessment of nicotine and tobacco delivery products Toxicology Letters
Year:2020
Tags:in vitro, endothelial cell migration assay, nicotine, glo, tobacco heating product, THP, cytotoxicity, migration assay, scratch wound, scratch, wound, Endothelial cell migration, blood vessels, cardiovascular disease,
Title:Results from a 2018 cross-sectional survey in Tokyo, Osaka and Sendai to assess tobacco and nicotine product usage after the introduction of heated tobacco products (HTPs) in Japan
Type:Publication
Author:Jason Adamson, Claudia Kanitscheider, Krishna Prasad, Oscar M. Camacho, Elisabeth Beyerlein, Yoga Keralapura Bhagavan, Christopher Proctor, James Murphy,
Description:Harm Reduction Journal
Year:2020
Tags:post-market surveillance, survey, cross-sectional survey, Tokyo, Osaka, Sendai, tobacco, nicotine, nicotine products, heated tobacco products, HTP, tobacco heating products, THP, Japan, glo,
Title:A 12-month randomised, controlled trial evaluating the effects of switching from smoking to using a Tobacco Heating Product on health effect indicators 90-Day Biomarkers of Exposure
Type:Poster
Author:Nathan Gale, Mike McEwan, George Hardie, James K. Ebajemito, Oscar M. Camacho, Christopher J. Proctor and James Murphy
Description:The Society for Research on Nicotine & Tobacco (SRNT)
Year:2020
Tags:SRNT, THP, biomarkers, tobacco heating products, glo, switching, cigarettes, clinical study, biomarkers of exposure,
Title:Control measures for assessing compliance in long-term Potentially Reduced Risk Product switching studies
Type:Poster
Author:Mike McEwan, Nathan Gale, George Hardie, Max Scherer, Nikola Pluym, James K. Ebajemito, Oscar M. Camacho, Allen Griffiths, James Murphy and Christopher J. Proctor
Description:The Society for Research on Nicotine & Tobacco (SRNT)
Year:2020
Tags:PRRP, switching studies, SRNT, THP, biomarkers, tobacco heating products, glo, switching, cigarettes, clinical study, biomarkers of exposure, compliance,
Title:Development of a method to measure cigarette, e-cigarette and tobacco heating product skin staining
Type:Poster
Author:Dalrymple, A.,Corke, S.,Sheehan, D.,Behrsing, H.,Coburn, S.
Description:SocietyofToxicology
Year:2019
Tags:Development of a method to measure cigarette, e-cigarette and tobacco heating product skin staining, SocietyofToxicology
Title:Assessment of the genotoxicity of a tobacco heating product relative to cigarette smoke using the in vitro micronucleus assay
Type:Poster
Author:Thorne, D.,Breheny, D.,Gaca, M.
Description:SocietyofToxicology
Year:2019
Tags:Assessment of the Genotoxicity of a Tobacco Heating Product Relative to Cigarette Smoke Using the In Vitro Micronucleus Assay, SocietyofToxicology
Title:Individual exposure levels in subjects switching to a tobacco heating product for 5 days
Type:Presentation
Author:Ebajemito, J.
Description:ENDS UK
Year:2019
Tags:BoE, Biomarkers of Exposure, switching, glo, THP, Tobacco heating product, exposure, ENDS UK
Title:Protocol for a Japanese nationwide repeated cross-sectional study to assess tobacco and nicotine product use behaviour after market introduction of tobacco heating products (THPs)
Type:Publication
Author:Adamson, J.,Kanitscheider, C.,Prasad, K.,Camacho, O.M.,Beyerlein, E.,Keralapura, Y.,Proctor C.,Murphy, J.
Description:F1000 Research
Year:2019
Tags:Post-market surveillance, Population studies, Cross sectional survey, Tobacco Heating Products, THPs, Harm reduction, glo, F1000 Research
Title:An assessment of nicotine kinetics and subjective effects of two tobacco heating products in comparison to cigarettes and a nicotine replacement therapy
Type:Poster
Author:Ebajemito, J.K.,Gale, N.,McEwan, M.,Hardie, G.,Murphy, J.,Proctor. C.J.
Description:SocietyofToxicology
Year:2019
Tags:An Assessment of Nicotine Kinetics and Subjective Effects of Two Tobacco Heating Products in Comparison to Cigarettes and a Nicotine Replacement Therapy, SocietyofToxicology
Title:A clinical study investigating changes in exposure to cigarette smoke chemicals in UK smokers who switch to using a tobacco heating product over a five day period
Type:Poster
Author:McEwan, M.,Gale, N.,Eldridge, A.,Errington, G.,Graff, D.,Murphy, J.,Proctor, C.,Fearon, I.
Description:SOT
Year:2018
Tags:THP, tobacco heating product, heat-not-burn, glo, neostick, SOT
Title:Reversibility of in vitro biological effects in cigarette smoke- exposed 3D lung tissues following switching to a tobacco heating product
Type:Poster
Author:Haswell, L.,Corke, S.,Jaunky, T.,Santopietro, S.,Baxter, A.,Thorne, D.,Minet, E.,Dalrymple, A.,Gaça, M.
Description:SOT
Year:2018
Tags:THP, tobacco heating product, heat-not-burn, glo, SOT
Title:Comparative in vitro toxicological evaluation of novel tobacco heating product
Type:Poster
Author:Thorne, D.,Breheny, D.,Kendall, B.,Proctor, C.,Gaca, M.
Description:SOT
Year:2018
Tags:THP, tobacco heating product, heat-not-burn, glo, SOT
Title:The effect of flavourings on the in vitro mutagenic and genotoxic potential of total particulate matter and gas vapour phase generated from a tobacco heating product
Type:Poster
Author:Crooks, I.,Le Godec, T.,Reynolds, L.,Neilson, L.,Scott, K.,Meredith, C.
Description:GTA
Year:2018
Tags:THP, Tobacco Heating Product, Heat-not-burn, GTA
Title:Assessment of the glo tobacco heating product (part 1): Aerosol composition and environmental emissions
Type:Poster
Author:Coburn, S.,Forster, M.,Wright, C.,Mariner, D.,Yuteri, C.,McAughey, J.,Murphy, J.,Proctor, C.
Description:GFN
Year:2018
Tags:THP, tobacco heating product, heat-not-burn, glo, neostick, GFN
Title:Assessment of the glo tobacco heating product (part 2): Traditional and 21st Century toxicology approaches
Type:Poster
Author:Breheny, D.,Adamson, J.,Baxter, A.,Crooks, I.,Jaunky, T.,Taylor, M.,Thorne, D.,Liu, C.,Murphy, J.,Proctor, C.,Gaca, M.
Description:GFN
Year:2018
Tags:THP, tobacco heating product, heat-not-burn, glo, neostick, GFN
Title:Assessment of the glo tobacco heating product (part 3): Clinical biomarkers of exposure
Type:Poster
Author:Gale, N.,McEwan, M.,Eldridge, A.,Camacho, O.,Murphy, J.,Proctor, C.
Description:GFN
Year:2018
Tags:THP, tobacco heating product, heat-not-burn, glo, neostick, GFN
Title:Assessment of the glo tobacco heating product: traditional and 21st century toxicology approaches
Type:Presentation
Author:Vardakou, I.
Description:LIVe
Year:2018
Tags:THP, tobacco heating product, heat-not-burn, glo, neostick, LIVe
Title:Thermo-oxidative degradation of aromatic flavour compounds under simulated tobacco heating product condition
Type:Publication
Author:Blazso, M.,Babinszki, B.,Czegeny Zs.,Barta-Rajnai, E.,Sebestyen, Z.,Jakab, E.,Nicol, J.,Liu, C.,McAdam, K.
Description:Journal of Analytical and Applied Pyrolysis
Year:2018
Tags:THP, Tobacco Heating Product, Heat-not-burn, Journal of Analytical and Applied Pyrolysis, BAT, A Better Tomorrow, Chuan Liu
Title:Assessment of tobacco heating product THP1.0. Part 8: Study to determine puffing topography, mouth level exposure and consumption among Japanese users
Type:Publication
Author:Jodie Gee, Krishna Prasad, Sandra Slayford, Adam Gray, Kathryn Nother, Anthony Cunningham, Eleni Mavropoulou, Christopher Proctor
Description:Assessment of tobacco heating product THP1.0. Part 8: Study to determine puffing topography, mouth level exposure and consumption among Japanese users Regulatory Toxicology and Pharmacology
Year:2018
Tags:tobacco heating product, THP, glo, puffing topography, topography, mouth level exposure, MLE, Japanese, Japan,
Title:Assessment of novel tobacco heating product THP1.0. Part 6: A comparative in vitro study using contemporary screening approaches
Type:Publication
Author:Mark Taylor, David Thorne, Tony Carr, Damien Breheny, Paul Walker, Christopher Proctor, Marianna Gaca,
Description:Assessment of novel tobacco heating product THP1.0. Part 6: A comparative in vitro study using contemporary screening approaches Regulatory Toxicology and Pharmacology
Year:2018
Tags:tobacco heating product, THP, glo, in vitro, screening approaches, Regulatory Toxicology and Pharmacology,
Title:Characterisation of a novel tobacco heating product THP1.0(T): Indoor air quality
Type:Poster
Author:Forster, M. ,McAughey, J. ,Liu, C. ,McAdam, K. ,Murphy, J. ,Proctor, C.
Description:Society for Research on Nicotine and Tobacco (SRNT)
Year:2017
Tags:THP, tobacco heating product, heat-not-burn, glo, aerosol, emissions, heated, IAQ, indoor air quality, toxicants, analytical chemistry, Harm reduction, Society for Research on Nicotine and Tobacco (SRNT)
Title:Assessment of exposure to smoke toxicants in users of the glo tobacco heating product
Type:Poster
Author:Fearon, I.,Gale, N.,Eldridge, A.,McEwan, M.
Description:Global Forum on Nicotine (GFN) Global Forum on Nicotine (GFN)
Year:2017
Tags:THP, tobacco heating product, heat-not-burn, glo, Biomarkers of Exposure, BoE, Switching Study, Biomarker, clinical, toxicant exposure, switch, PK, pharmacokinetic, Global Forum on Nicotine (GFN)
Title:Novel nicotine aerosol delivery devices – the impact of a tobacco heating product and e-cigarettes on indoor air quality
Type:Poster
Author:McAughey, J.,Caner, Y.,Forster, M.,Margham, J.
Description:European Aerosol Conference (EAC)
Year:2017
Tags:aerosol, emissions, heated, IAQ, indoor air quality, toxicants, analytical chemistry, Harm reduction, vaping, vapour, e-cigarettes, e-cig, European Aerosol Conference (EAC)
Title:In vitro dosimetric and cytotoxic assessment of a commercially available tobacco heating product (THP) versus a reference cigarette.
Type:Poster
Author:Adamson, J.,Jaunky, T.,Santopietro, S.,Terry, A.,Throne, D.,Breheny, D.,Gaca, M.
Description:European Aerosol Conference (EAC)
Year:2017
Tags:THP, tobacco heating product, heat-not-burn, glo, neostick, in vitro, aerosol, dosimetry, exposure, exposure systems, air-liquid interface, cell culture, cytotoxicity, toxicology, European Aerosol Conference (EAC)
Title:The pre-clinical assessment of a tobacco heating product (glo)
Type:Poster
Author:Murphy, J.,Thorne, D.,Breheny, D.,Gaca, M.,Liu, C.,Proctor, C.
Description:Sociedade Brasileira de Toxicologia (SBTOX)
Year:2017
Tags:THP, tobacco heating product, heat-not-burn, glo, in vitro, harm reduction, pre-clinical, air-liquid interface, exposure chamber, exposure systems, High content screening, mutagenicity, cytotoxicity, genotoxicity, WA, TPM, whole aerosol, total particulate matter, Sociedade Brasileira de Toxicologia (SBTOX)
Title:Exposure to cigarette smoke toxicants in smokers who switch to using the glo tobacco heating product
Type:Poster
Author:Gale, N.,Fearon, I.,McEwan, M.,Murphy, J.,Proctor, C.
Description:Sociedade Brasileira de Toxicologia (SBTOX)
Year:2017
Tags:THP, tobacco heating product, heat-not-burn, glo, Biomarkers of Exposure, BoE, Switching Study, Biomarker, clinical, toxicant exposure, switch, PK, pharmacokinetic, Sociedade Brasileira de Toxicologia (SBTOX)
Title:Characterising key thermophysical parameters to heat and no burn tobacco in a tobacco heating product glo
Type:Presentation
Author:Jakal, B.,Eaton, D.,Forster, M.,Nicol, J.,Liu, C.,McAdam, K.,Murphy, J.,Proctor, C.
Description:PIC Congress
Year:2017
Tags:THP, tobacco heating product, heat-not-burn, glo, neostick, assessment framework, combustion, pyrolysis, aerosol, deposition, thermal degradation, heated, PIC Congress
Title:A clinical study in Japanese smokers investigating changes in exposure to cigarette smoke chemicals in participants who switch to using a tobacco heating product for a five day period
Type:Presentation
Author:McEwan, M.,Eldridge, A.,Gale, N.,Errington, G.,McDermott, S.,Glew, J.,Hedge, A.,Murphy, J.,Proctor, C.,Fearon, I.
Description:CORESTA
Year:2017
Tags:THP, tobacco heating product, heat-not-burn, glo, neostick, Biomarkers of Exposure, BoE, Switching Study, Biomarker, clinical, toxicant exposure, switch, PK, pharmacokinetic, CORESTA
Title:A randomised, controlled, two-centre open-label study in healthy Japanese subjects to evaluate the effect on biomarkers of exposure of switching from a conventional cigarette to a tobacco heating product
Type:Publication
Author:Gale, N.,McEwan, M.,Sherwood, N.,Eldridge, A.,Bowen, E.,McDermott, S.,Holmes, E.,Hedge, A.,Hossack, S.,Camacho, O.,Errington, G.,McAughey, J.,Murphy, J.,Liu, C.,Proctor, C.,Fearon, I.
Description:BMC Public Health
Year:2017
Tags:THP, tobacco heating product, heat-not-burn, glo, neostick, clinical, Switching Study, toxicant exposure, emissions, Biomarkers of Exposure. BoE, Biomarkers of Biological Effect, BOBE, harm reduction, BMC Public Health
Title:Assessment of tobacco heating product THP1.0. Part 1: Series introduction
Type:Publication
Author:Proctor, C.
Description:Regulatory Toxicology and Pharmacology
Year:2017
Tags:harm reduction, assessment framework, risk continuum, THP, tobacco heating product, heat-not-burn, glo, neostick, Regulatory Toxicology and Pharmacology
Title:Assessment of tobacco heating product THP1.0. Part 2: Product design, operation and thermophysical characterisation
Type:Publication
Author:Eaton, D.,Blerta, J.,Forster, M.,Nicol, J.,Mavropoulou, E.,Scott, K.,Liu, C.,McAdam, K.,Murphy, J.,Proctor, C.
Description:Regulatory Toxicology and Pharmacology
Year:2017
Tags:THP, tobacco heating product, heat-not-burn, glo, neostick, assessment framework, combustion, pyrolysis, aerosol, deposition, thermal degradation, heated, Regulatory Toxicology and Pharmacology
Title:Assessment of novel tobacco heating product THP1.0. Part 3: Comprehensive chemical characterisation of harmful and potentially harmful aerosol emissions
Type:Publication
Author:Forster, M.,Fiebelkorn, S.,Yuteri, C.,Mariner, D.,Liu, C.,Wright, C.,McAdam, K.,Murphy, J.,Proctor, C.
Description:Regulatory Toxicology and Pharmacology
Year:2017
Tags:THP, tobacco heating product, heat-not-burn, glo, neostick, aerosol, emissions, heated, toxicants, analytical chemistry, Harm reduction, HPHCs, Harmful and Potentially Harmful Constituents, Regulatory Toxicology and Pharmacology
Title:Assessment of tobacco heating product THP1.0. Part 4: Characterisation of indoor air quality and odour
Type:Publication
Author:Forster, M.,McAughey, J.,Prasad, K.,Mavropoulou, E.,Proctor, C.
Description:Regulatory Toxicology and Pharmacology
Year:2017
Tags:THP, tobacco heating product, heat-not-burn, glo, neostick, aerosol, emissions, heated, IAQ, indoor air quality, toxicants, analytical chemistry, Harm reduction, Regulatory Toxicology and Pharmacology
Title:Assessment of tobacco heating product THP1.0. Part 5: In vitro dosimetric and cytotoxic assessment
Type:Publication
Author:Jaunky, T.,Adamson, J.,Santopietro, S.,Terry, A.,Thorne, D.,Breheny, D.,Proctor, C.,Gaca, M.
Description:Regulatory Toxicology and Pharmacology
Year:2017
Tags:THP, tobacco heating product, heat-not-burn, glo, neostick, in vitro, aerosol, dosimetry, exposure, exposure systems, air-liquid interface, cell culture, cytotoxicity, toxicology, Regulatory Toxicology and Pharmacology
Title:Assessment of novel tobacco heating product THP1.0. Part 7: Comparative in vitro toxicological evaluation
Type:Publication
Author:Thorne, D.,Breheny, D.,Proctor, C.,Gaca, M.
Description:Regulatory Toxicology and Pharmacology
Year:2017
Tags:THP, tobacco heating product, heat-not-burn, glo, neostick, in vitro, exposure, toxicants, CVD, cardiovascular disease, lung cancer, systems biology, cytotxicity, DNA, genotoxicity, mutagenicity, reduced risk, harm reduction, pre-clinical, Regulatory Toxicology and Pharmacology
Title:Assessment of tobacco heating product THP1.0. Part 9: The placement of a range of next-generation products on an emissions continuum relative to cigarettes via pre-clinical assessment studies
Type:Publication
Author:Murphy, J.,Liu, C.,McAdam, K.,Gaca, M.,Prasad, K.,Camacho, O.,McAughey, J.,Proctor, C.
Description:Regulatory Toxicology and Pharmacology
Year:2017
Tags:THP, tobacco heating product, heat-not-burn, glo, neostick, emissions, risk continuum, harm reduction, assessment framework, pre-clinical, exposure, Regulatory Toxicology and Pharmacology
Title:Headspace solid-phase microextraction coupled to comprehensive two-dimensional gas chromatography–time-of-flight mass spectrometry for the analysis of aerosol from tobacco heating product
Type:Publication
Author:Savareear, B.,Lizak, R.,Brokl, M.,Wright, C.,Liu, C.,Focant, J F.
Description:Journal of Chromotography A
Year:2017
Tags:THP, tobacco heating product, heat-not-burn, glo, neostick, analytical chemistry, gas chromatography, mass spectrometry, toxicants, aerosol, particulate phase, Journal of Chromotography A
Title:Thermal behaviour of selected flavour ingredients and additives under simulated cigarette combustion and tobacco heating conditions
Type:Publication
Description:Journal of Analytical and Applied Pyrolysis
Year:2016
Tags:thp, tobacco heating product, heat-not-burn, themo, pyrolysis, gas chromatography, mass spectrometry, temperature, decompostion, degradation, Journal of Analytical and Applied Pyrolysis
Title:The application of an exposure system developed for the in vitro assessment of electronic cigarettes and prototype tobacco heating products
Type:Poster
Author:Green, H.,Patel, K.,Jaunky, T.,Santopietro, S.,Camacho, O.,Azzopardi, D.
Description:European Aerosol Conference (EAC)
Year:2015
Tags:The application of an exposure system developed for the in vitro assessment of electronic cigarettes and prototype tobacco heating products, European Aerosol Conference (EAC)
Title:Assessment of an in vitro model of lung epithelial stress responses following exposure to aqueous extracts generated from a tobacco heating product and an electronic cigarette
Type:Poster
Author:Taylor, M.,Carr, T.,Oke, T.,Jaunky, T.
Description:Eurotox 2015
Year:2015
Tags:Assessment of an in vitro model of lung epithelial stress responses following exposure to aqueous extracts generated from a tobacco heating product and an electronic cigarette, Eurotox 2015
Title:The in vitro assessment of a novel vaping technology
Type:Publication
Author:D.Breheny, D.Thorne, A.Baxter, S.Bozhilova, T.Jaunky, S.Santopietro, M.Taylor, A.Terry, M.Gaca
Description:The in vitro assessment of a novel vaping technology Toxicology Reports
Year:2020
Tags:in vitro assessment, novel vaping technology, vapour, vaping, iSwitch, toxicants,
Title:Comprehensive Chemical Characterization of the Aerosol Emissions of a Vaping Product Based on a New Technology
Type:Publication
Author:James Nicol, Rory Fraser, Liam Walker, Chuan Liu, James Murphy, Christopher Proctor,
Description:Comprehensive Chemical Characterization of the Aerosol Emissions of a Vaping Product Based on a New Technology Chemical Research in Toxicology
Year:2020
Tags:Vype, iSwitch, chemical characterization, Chemical Research in Toxicology, aerosol, vapour, vaping, vapour products, vape, coil and wick, distiller plate, technology,
Title:Application of next generation in vitro approaches for the assessment of e-cigarettes
Type:Poster
Author:Gaca, M.,Lowe, F.,Minet, E.,Thorne, D.,Breheny, D.
Description:GFN
Year:2019
Tags:in vitro, e-cigarettes, vaping, vapour, GFN
Title:Can innovation in vapour products bring more satisfaction with lower toxicant levels?
Type:Presentation
Author:Proctor, C.
Description:ISoNTech
Year:2019
Tags:iSwitch, ePen 3, Vype, vapour, vaping, ePen, e-cigarette, ISoNTech
Title:Assessment of enamel discoloration in vitro following exposure to cigarette smoke and emissions from novel vapour and tobacco heating products
Type:Publication
Author:Dalrymple, A.,Badrock, T C.,Terry, A.,Barber, M.,Hall, P.,Thorne, D.,Gaca, M.,Coburn, S.,Proctor, C.
Description:American Journal of Dentistry
Year:2018
Tags:THP, Tobacco Heating Product, Heat-not-burn, American Journal of Dentistry
Title:Population modelling assessing the health effects of launching tobacco heated products in Japan
Type:Poster
Author:Camacho, O M. ,Hill, A. ,Adamson, J. ,Keralapura, Y. ,Prasad, K. ,Murphy, J. ,Proctor, C.
Description:Society for Research on Nicotine and Tobacco (SRNT)
Year:2019
Tags:THP, tobacco heating product, heat-not-burn, glo, neostick, Society for Research on Nicotine and Tobacco (SRNT)
Title:Using a population model to assess the impact of "dual use" of ENDS with conventional cigarettes
Type:Poster
Author:Hill, A.,Fiebelkorn, S.,Murphy, J.,Proctor, C.,Camacho, O.
Description:Global Forum on Nicotine (GFN) Global Forum on Nicotine (GFN)
Year:2017
Tags:Population studies, modelling, population health, public health, Smoking Prevalence, Mortality Rates, Smoking Initiation, Relative Risks, model, modeling, population, dual user, dual users, relapse rate, vaping, vapour, e-cigarettes, e-cig, Global Forum on Nicotine (GFN)
Title:A system dynamics modelling approach to assess the impact of launching a new nicotine product on population health outcomes
Type:Publication
Author:Hill, A.,Camacho, O.
Description:Regulatory Toxicology and Pharmacology
Year:2017
Tags:vaping, vapour, e-cigarettes, e-cig, systems dynamics, model, modelling, modeling, Population studies, Nicotine, population health, Regulatory Toxicology and Pharmacology
Title:Population model to estimate health effects of launching a NGP in a market
Type:Presentation
Author:Camacho, O.
Description:Tobacco Science Research Conference (TSRC)
Year:2015
Tags:Population Model to Estimate Health Effects of Launching a NGP in a Market , Illustrated with e-cigarettes and all-cause mortality rates in the UK, Tobacco Science Research Conference (TSRC)
Title:The composition of contemporary American and Swedish smokeless tobacco products
Type:Publication
Author:McAdam, K.G.,Kimpton, H.,Faizi, A.,Porter, A.,Rodu, B.
Description:BMC Chemistry
Year:2019
Tags:The composition of contemporary American and Swedish smokeless tobacco products, BMC Chemistry
Title:Pathway-based predictive approaches for non-animal assessment of acute inhalation toxicity
Type:Publication
Author:Clippinger, A.J.,Allen, D.,Behrsing, H.,BéruBé, K.A.,Bolger, M.B.,Casey, W.,DeLorme, M.,Gaça, M.,Gehen, S.C.,Glover, K.,Hayden, P.,Hinderliter, P.,Hotchkiss, J.A.,Iskandar, A.,Keyser, B.,Luettich, K.,Ma-Hock, L.,Maionek, A.G.,Jarabeky, A.M.
Description:Toxicology in Vitro
Year:2019
Tags:acute inhalation toxicity, in vitro, in silico, ex vivo, quantitative structure-activity relationships, QSAR, adverse outcome pathway, aggregate exposure pathway, dosimetry, integrated approach to testing and assessment, IATA, risk assessment, RAI, Reynolds, Toxicology in Vitro
Title:Ethyl carbamate in Swedish and American smokeless tobacco products and some factors affecting its concentration
Type:Publication
Author:McAdam, K.,Vas, C.,Kimpton, H.,Faizi, A.,Liu, C.,Porter, A.,Synnerdahl, T.,Karlsson, P.,Rodu, B.
Description:Chemistry Central Journal
Year:2018
Tags:Ethyl carbamate in Swedish and American smokeless tobacco products and some factors affecting its concentration, Chemistry Central Journal
Title:Analysis of coumarin and angelica lactones in smokeless tobacco products
Type:Publication
Author:McAdam, K.,Enos, T.,Goss, C.,Kimpton, H.,Falzi, A.,Edwards, S.,Wright, C.,Porter, A.,Rodu, B.
Description:Chemistry Central Journal Chemistry Central Journal
Year:2018
Tags:Coumarin, angelica, lactones, smokeless tobacco products, Chemistry Central Journal, Kevin McAdam
Title:Comprehensive survey of radionuclides in contemporary smokeless tobacco products
Type:Publication
Author:McAdam, K.,Kimpton, H.,Porter, A.,Liu C.,Faizi, A.,Mola, M.,McAughey, J.,Rodu, B.
Description:Chemistry Central Journal
Year:2017
Tags:Comprehensive survey of radionuclides in contemporary smokeless tobacco products, Chemistry Central Journal
Title:Development of a biologically-representative laboratory analysis system for the measurement of emissions from snus during use
Type:Poster
Author:Gale, N.,Byrom, D.
Description:Cooperation Centre for Scientific Research Relative to Tobacco (CORESTA)
Year:2014
Tags:Development of a biologically-representative laboratory analysis system for the measurement of emissions from snus during use, Cooperation Centre for Scientific Research Relative to Tobacco (CORESTA)
Title:The acrylamide content of smokeless tobacco products
Type:Poster
Author:McAdam, K.,Kimpton, H.,Vas, C.,Rushforth, D.,Rodu, B.
Description:Society for Research on Nicotine and Tobacco (SRNT)
Year:2014
Tags:The acrylamide content of smokeless tobacco products SRNT 2014, Society for Research on Nicotine and Tobacco (SRNT)
Title:Multi-analyte approach for determining the extraction of tobacco constituents from pouched snus by consumers during use
Type:Publication
Author:Digard, H.,Gale, N.,Errington, G.,Peters, N.,McAdam, K.
Description:Chemistry Central Journal 7:55
Year:2013
Tags:Snus, Dosimetry, Exposure assessment, Multi-analyte chemical analysis, Nicotine, Tobacco-specific nitrosamines, Chemistry Central Journal
Title:Polycyclic aromatic hydrocarbons in US and Swedish smokeless tobacco products
Type:Publication
Author:McAdam, K.,Faizi, A.,Kimpton, H.,Porter, A.,Rodu, B.
Description:Chemistry Central Journal 7:151
Year:2013
Tags:Smokeless tobacco, Snus, Polycyclic aromatic hydrocarbons, Chemistry Central Journal
Title:Combustible and non-combustible tobacco product preparations differentially regulate human peripheral blood mononuclear cell functions
Type:Publication
Author:Arimilli, S.,Damratoski, B.E.,Prasad, G.L.
Description:Toxicology in Vitro
Year:2013
Tags:Tobacco product preparations, TPPs, T cells, NK cells, PBMCs, LPS, Cytotoxicity assay, combustibles, cigarettes, smokeless, snus, Toxicology in Vitro
Title:Determination of nicotine absorption from multiple tobacco products and nicotine gum
Type:Publication
Author:Digard, H.,Proctor, C.,Kulasekaran, A.,Malmqvist, U.,Richter, A.
Description:Nicotine and Tobacco Research 15(1):255-261
Year:2013
Tags:Snus, smokeless tobacco, nicotine absorption, nicotine gum, Nicotine and Tobacco Research
Title:Influence of usage time on exposure of snus users to nicotine, NNN and NNK from snus pouches
Type:Poster
Author:Gale, N.,Digard, H.,McAdam, K.,Williamson, J.
Description:Society for Research on Nicotine and Tobacco (SRNT)
Year:2012
Tags:Influence of usage time on exposure of snus users to nicotine, NNN and NNK from snus pouches, Society for Research on Nicotine and Tobacco (SRNT)
Title:Determination of hydrazine in smokeless tobacco products by GC-MS
Type:Presentation
Author:Davis, P.,Kimpton, H.,Wright, C.,McAdam, K.
Description:Cooperation Centre for Scientific Research Relative to Tobacco (CORESTA)
Year:2011
Tags:Determination of hydrazine in smokeless tobacco products by GC-MS, Cooperation Centre for Scientific Research Relative to Tobacco (CORESTA)
Title:A comparison of consumption behaviour in Swedish users of loose and portion snus
Type:Poster
Author:Richter, A.,Proctor, C.,Digard, H.,Errington, G.,McAdam, K.
Description:Cooperation Centre for Scientific Research Relative to Tobacco (CORESTA)
Year:2009
Tags:British American Tobacco Group Research and Development, CORESTA, A comparison , consumption behaviour , Swedish, loose , portion , snus, Cooperation Centre for Scientific Research Relative to Tobacco (CORESTA)
Title:Assessment of the irritation potential of Swedish snus ingredients using the epioral™ tissue model
Type:Poster
Author:Neilson, L.,Faux, S.,Hinchcliffe, S.,Jai, T.,Meredith, C.
Description:Society of Toxicology (SOT)
Year:2009
Tags:British American Tobacco, Group Research and Development, SOT, Irritation , Swedish snus , ingredients , epioral™ , tissue model., Society of Toxicology (SOT)
Title:A comparison of radioactive elements in US and Swedish smokeless tobacco products
Type:Poster
Author:Mola, M.,Faizi, A.,Rodu, B.,Mcadam, K.,Benzing, R.,Prior, G.
Description:Tobacco Science Research Conference (TSRC)
Year:2009
Tags:British American Tobacco, Group Research and Development, TSRC, Comparison, Radioactive elements , US, Swedish , Smokeless , Tobacco products., Tobacco Science Research Conference (TSRC)
Title:Cytotoxicity and genotoxicity testing of extracts of snus tobacco
Type:Poster
Author:Neilson, L.,Dillon, D.,Pearce, H.,Stone, V.,Meredith, C.
Description:European Societies of Toxicology (EUROTOX)
Year:2009
Tags:British American Tobacco, Group Research and Development, EUROTOX, Cytotoxicity, Genotoxicity, Testing , Extracts , Snus Tobacco., European Societies of Toxicology (EUROTOX)
Title:A consumption survey of snus users in Sweden
Type:Poster
Author:Proctor, C.,Massey, E.,Sandi, D.,Digard, H.,Meredith, C.,Hartmann, R.
Description:Society for Research on Nicotine and Tobacco (SRNT)
Year:2008
Tags:A consumption survey of snus users in Sweden, Society for Research on Nicotine and Tobacco (SRNT)
Title:Analysis of tobacco constituent extraction by snus users
Type:Poster
Author:McAdam, K.,Digard, H.,Williamson, J.,Proctor, C.
Description:Society for Research on Nicotine and Tobacco (SRNT)
Year:2008
Tags:Analysis of tobacco constituent extraction by snus users, Society for Research on Nicotine and Tobacco (SRNT)
Title:Should the health community promote smokeless tobacco (snus): Comments from British American Tobacco
Type:Publication
Author:Williamson, J.,Proctor, C.
Description:PLoS Medicine 4(10):1703-1705
Year:2007
Tags:Health, smokeless tobacco, snus, harm reduction, PLoS Medicine
Title:A cross-category puffing topography, mouth level exposure and consumption study among Italian users of tobacco and nicotine products
Type:Publication
Author:Joshua Jones, Sandra Slayford, Adam Gray, Kathryn Brick, Krishna Prasad, Christopher Proctor
Description:Scientific Reports
Year:2020
Tags:cross-category puffing topography, topography, puffing, mouth level exposure, MLE, Italian, tobacco, nicotine, Italy, e-cigarette, electronic cigarettes, vapour, iSwitch, glo, THP, tobacco heating product,
Title:Assessment of tobacco heating product THP 1.0. Part 8: Study to determine puffing topography, mouth level exposure and consumption among Japanese users
Type:Publication
Author:Gee, J.,Prasad, K.,Slayford, S.,Gray, A.,Brick, K.,Cunningham, A.,Mavropoulou, E.,Proctor, C.
Description:Regulatory Toxicology and Pharmacology
Year:2017
Tags:THP, tobacco heating product, heat-not-burn, glo, neostick, puffing, mouth level exposure, MLE, topography, behaviour, consumer, puff duration, regime, Regulatory Toxicology and Pharmacology
Title:Development, validation and application of a device to measure e-cigarette users’ puffing topography
Type:Publication
Author:Cunningham, A.,Slayford, S.,Vas, C.,Gee, J. ,Costigan, S. ,Prasad, K.
Description:Scientific Reports
Year:2016
Tags:puffing, topography, behaviour, MLE, mouth level exposure, dosimetry, exposure, emissions, regime, Scientific Reports
Title:Development and validation of a device to measure e-cigarette users’ puffing topography
Type:Poster
Author:Cunningham, A.,Slayford, S.,Vas, C.,Gee, J.,Costigan, S.,Prasad, K.
Description:Global Forum on Nicotine (GFN)
Year:2015
Tags:Development & validation of a device to measure e-cigarette users’ puffing topography, Global Forum on Nicotine (GFN)
Title:A Device to Measure a Smoker’s Puffing Topography and Real-Time Puff-By-Puff “Tar” Delivery
Type:Publication
Author:Slayford, S,Frost, B
Description:Contributions to Tobacco Research
Year:2014
Tags:Flow, duration, volume, puffing behaviour, LED, photodetector, estimation of tar, Contributions to Tobacco Research
Title:A comparison of the Plowshare Cressmicro smoking topography analyser with a proprietary smoking analyser
Type:Poster
Author:Mariner, D.,Slayford, S.,Nother, K.,Shepperd, C.
Description:Society for Research on Nicotine and Tobacco (SRNT)
Year:2008
Tags:BAT R&D, British American Tobacco Research and Development, BAT Science, Tobacco industry research, Plowshare Cressmicro, Smoking analysers, Smoking behaviour, Society for Research on Nicotine and Tobacco (SRNT)
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