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  • Biomarkers of Exposure and Potential Harm in Exclusive Users of Electronic Cigarettes and Current, Former and Never-Smokers: A Cross-Sectional Study Protocol
    Vapour
    Nathan Gale
    May 2022
    Biomarkers of Exposure and Potential Harm in Exclusive Users of Electronic Cigarettes and Current, Former and Never-Smokers: A Cross-Sectional Study Protocol
  • Pilot study to determine differences in breath odour between cigarette and e-cigarette consumers
    Vapour
    Annette Dalrymple
    February 2022
    Pilot study to determine differences in breath odour between cigarette and e-cigarette consumers
  • Application of ToxTracker for the toxicological assessment of tobacco and nicotine delivery products
    Vapour
    David Smart
    January 2022
    Application of ToxTracker for the toxicological assessment of tobacco and nicotine delivery products

Take a look at our peer-reviewed publications along with our posters, presentations and conference materials. Material published by Reynolds American Inc. from 2018 onwards can also be accessed through our library.

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Title: Chemical characterisation of the vapour emitted by an e-cigarette using a ceramic wick-based technology
Type: Publication
Author: M. Isabel Pinto, J. Thissen, N. Hermes, A. Cunningham, H. Digard & J. Murphy
Description: Chemical characterisation of the vapour emitted by an e-cigarette using a ceramic wick-based technology Scientific Reports
Year: 2022
Tags: Vuse ePod, vapour, vaping, Chemical characterisation of the vapour emitted by an e-cigarette using a ceramic wick-based technology, science behind vaping, e-cigarette chemistry, BAT, A Better Tomorrow, M. Isabel Pinto, J. Thissen, N. Hermes, A. Cunningham, H. Digard & J. Murphy, Nature, Scientific Reports,
Title: Biomarkers of Exposure and Potential Harm in Exclusive Users of Electronic Cigarettes and Current, Former and Never-Smokers: A Cross-Sectional Study Protocol
Type: Publication
Author: Nathan Gale, Linsey Ellen Haswell, Michael McEwan, David Azzopardi, Jesse Thissen, George Hardie
Description: Biomarkers of Exposure and Potential Harm in Exclusive Users of Electronic Cigarettes and Current, Former and Never-Smokers: A Cross-Sectional Study Protocol Journal of Health and Environmental Research
Year: 2022
Tags: Vuse, vapour, ePod, ePen, Cross-sectional study, Biomarkers of Exposure, Potential Harm, e-cigarettes, Electronic Cigarettes, Protocol, ENDS, Biomarkers of Exposure and Potential Harm in Exclusive Users of Electronic Cigarettes and Current, Former and Never-Smokers: A Cross-Sectional Study Protocol, Journal of Health and Environmental Research, Nathan Gale, Linsey Ellen Haswell, Michael McEwan, David Azzopardi, Jesse Thissen, George Hardie,
Title: Pilot study to determine differences in breath odour between cigarette and e-cigarette consumers
Type: Publication
Author: Annette Dalrymple, Steven Coburn, Marianne Brandt, George Hardie, James Murphy,
Description: Pilot study to determine differences in breath odour between cigarette and e-cigarette consumers Scientific Reports
Year: 2022
Tags: Pilot study, breath odour, breath, cigarettes, e-cigarettes, vapour, vaping, ePen 3, Vuse, Vuse 3Pen, Germany, Scientific Reports, Annette Dalrymple, Steven Coburn, Marianne Brandt, George Hardie, James Murphy
Title: Application of ToxTracker for the toxicological assessment of tobacco and nicotine delivery products
Type: Publication
Author: David E.Smart, Stela Bozhilova, Fabio Miazzi, Linsey E.Haswell, Marianna D.Gaca, David Thorne, Damien Breheny,
Description: Application of ToxTracker for the toxicological assessment of tobacco and nicotine delivery products Toxicology Letters,
Year: 2022
Tags: ToxTracker, toxicological assessment, tobacco, nicotine delivery products, vaping, tobacco heating products, glo, ePen 3, Vuse ePen 3, Vuse, cigarettes, smoking, toxicity, David E.Smart, Stela Bozhilova, Fabio Miazzi, Linsey E.Haswell, Marianna D.Gaca, David Thorne, Damien Breheny, Toxicology Letters,
Title: A 3D in vitro comparison of two undiluted e-cigarette aerosol generating systems
Type: Publication
Author: E.Bishop, A.Terry, N.East, D.Breheny, M.Gaça, D.Thorne,
Description: A 3D in vitro comparison of two undiluted e-cigarette aerosol generating systems Toxicology Letters
Year: 2022
Tags: 3D in vitro comparison, e-cigarettes, vaping, vapour, aerosol generating systems, Vitrocell VC10, Borgwaldt LM4E, in vitro e-cigarette exposure, MucilAir, E.Bishop, A.Terry, N.East, D.Breheny, M.Gaça, D.Thorne, ePen 3, Vuse ePen 3, eBox, Vuse, Toxicology Letters,
Title: Transcriptomic Response of Primary Human Bronchial Cells to Repeated Exposures of Cigarette and ENDS Preparations
Type: Publication
Author: Rachael E Rayner, Jack Wellmerling, Patrudu Makena, Jing Zhao, G L Prasad, Estelle Cormet-Boyaka,
Description: Transcriptomic Response of Primary Human Bronchial Cells to Repeated Exposures of Cigarette and ENDS Preparations Cell Biochemistry and Biophysics
Year: 2022
Tags: Transcriptomic Response, Primary Human Bronchial Cells, Repeated Exposure, Cigarettes, smoke, nicotine, ENDS, electronic nicotine delivery systems, vapour, vaping, Reynolds American, RAI, Rachael E Rayner, Jack Wellmerling, Patrudu Makena, Jing Zhao, G L Prasad, Estelle Cormet-Boyaka, Cell Biochemistry and Biophysics,
Title: Investigating the Health Effects of 3 Coexisting Tobacco-Related Products Using System Dynamics Population Modeling: An Italian Population Case Study
Type: Publication
Author: Oscar M Camacho, Andrew Hill, Stacy Fiebelkorn, Aaron Williams, James Murphy,
Description: Investigating the Health Effects of 3 Coexisting Tobacco-Related Products Using System Dynamics Population Modeling: An Italian Population Case Study Frontiers in Public Health
Year: 2021
Tags: Investigating the Health Effects of 3 Coexisting Tobacco-Related Products Using System Dynamics Population Modeling: An Italian Population Case Study, tobacco heating products, THP, glo, vapour products, Vuse, Vype, vaping, Oscar M Camacho, Andrew Hill, Stacy Fiebelkorn, Aaron Williams, James Murphy, Italy, Italian study, Frontiers in Public Health,
Title: Evidence From the Scientific Assessment of Electronic Cigarettes and Their Role in Tobacco Harm Reduction
Type: Publication
Author: Camacho, Oscar M., Ebajemito, James K., Coburn, Steven, Prasad, Krishna, Costigan, Sandra and Murphy, James J
Description: Evidence From the Scientific Assessment of Electronic Cigarettes and Their Role in Tobacco Harm Reduction Contributions to Tobacco & Nicotine Research
Year: 2021
Tags: Evidence From the Scientific Assessment of Electronic Cigarettes and Their Role in Tobacco Harm Reduction, vaping, vapour, vape, is vaping safe, smoking, quit smoking, BAT, A Better Tomorrow, science behind vaping, science on vaping, Oscar Camacho, Contributions to Tobacco & Nicotine Research,
Title: Enamel staining with e-cigarettes, tobacco heating products and modern oral nicotine products compared with cigarettes and snus: An in vitro study
Type: Publication
Author: Annette Dalrymple, Emma-Jayne Bean, Thomas C. Badrock, Randy A. Weidman, Jesse Thissen, Steven Coburn, James Murphy
Description: American Journal of Dentistry
Year: 2021
Tags: Staining, e-cigarettes, tobacco heating products, THPs, modern oral products, MOPs, nicotine, cigarettes, snus, in vitro, BAT, A Better Tomorrow, American Journal of Dentistry, Annette Dalrymple, Dalrymple
Title: Scientific Review Article Summary: A comprehensive evidence review of electronic cigarettes and their role in tobacco harm reduction
Type: Publication
Author: BAT
Description: Scientific Review Article Summary: A comprehensive evidence review of electronic cigarettes and their role in tobacco harm reduction
Year: 2021
Tags: vaping, vapour, scientific evidence, vapour science, tobacco, tobacco harm reduction, scientific review, BAT, A Better Tomorrow, R&D,
Title: Application of text mining to develop AOP-based mucus hypersecretion genesets and confirmation with in vitro and clinical samples
Type: Publication
Author: Emmanuel Minet, Linsey E. Haswell, Sarah Corke, Anisha Banerjee, Andrew Baxter, Ivan Verrastro
Description: Application of text mining to develop AOP-based mucus hypersecretion genesets and confirmation with in vitro and clinical samples Scientific Reports
Year: 2021
Tags: text mining, AOP-based mucus hypersecretion genesets, in vitro, clinical samples, lung function, COPD, Mucus hypersecretion, tobacco, smoking, cigarettes, disease, systems biology, gene expression, Emmanuel Minet, Linsey E. Haswell, Sarah Corke, Anisha Banerjee, Andrew Baxter, Ivan Verrastro, Scientific Reports, Nature,
Title: Impact of cigarette versus electronic cigarette aerosol conditioned media on aortic endothelial cells in a microfluidic cardiovascular model
Type: Publication
Author: Om Makwana, Gina A. Smith, Hannah E. Flockton, Gary P. Watters, Frazer Lowe, Damien Breheny
Description: Scientific Reports
Year: 2021
Tags: Electronic cigarette, vaping, e-cigarette, cigarette, Scientific Reports, BAT, A Better Tomorrow, Damien Breheny
Title: The Evolving E-cigarette: Comparative Chemical Analyses of E-cigarette Vapor and Cigarette Smoke
Type: Publication
Author: Anthony Cunningham, Kevin McAdam, Jesse Thissen, Helena Digard
Description: Frontiers in Toxicology
Year: 2020
Tags: e-cigarette, vapor, vapour, cigarette, BAT, A Better Tomorrow, Frontiers in Toxicology, Anthony Cunningham, ePen 3, Vype, chemistry, chemical analysis,
Title: A randomised controlled single-centre open-label pharmacokinetic study to examine various approaches of nicotine delivery using electronic cigarettes
Type: Publication
Author: James K. Ebajemito, Michael McEwan, Nathan Gale, Oscar M. Camacho, George Hardie and Christopher J. Proctor
Description: Scientific Reports
Year: 2020
Tags: electronic cigarettes, e-cigarettes, Vype ePen 3, vape, Scientific Reports, BAT, A Better Tomorrow, James K. Ebajemito, pharmacokinetic, ePen, ePen 2,
Title: Optimization of aqueous aerosol extract (AqE) generation from e-cigarettes and tobacco heating products for in vitro cytotoxicity testing
Type: Publication
Author: Stela Bozhilova, Andrew Baxter, Emma Bishop, Damien Breheny, David Thorne, Paul Hodges, Marianna Gaça
Description: Toxicology Letters
Year: 2020
Tags: e-cigarettes, tobacco heating products, Toxicology Letters, Stela Bozhilova
Title: Development of a novel method to measure material surface staining by cigarette, e-cigarette or tobacco heating product aerosols
Type: Publication
Author: Annette Dalrymple, Thomas C.Badrock, Anya Terry, Emma-Jayne Bean, Mark Barber, Peter J.Hall, Steven Coburn, John McAughey, James Murphy
Description: Heliyon
Year: 2020
Tags: staining, surface staining, novel method, material surface staining, cigarette, e-cigarette, tobacco heating products, aerosols, glo, Vype, THP, vapour, vaping, glo pro, glo sens, Vype ePen,
Title: The in vitro assessment of a novel vaping technology
Type: Publication
Author: D.Breheny, D.Thorne, A.Baxter, S.Bozhilova, T.Jaunky, S.Santopietro, M.Taylor, A.Terry, M.Gaca
Description: The in vitro assessment of a novel vaping technology Toxicology Reports
Year: 2020
Tags: in vitro assessment, novel vaping technology, vapour, vaping, iSwitch, toxicants,
Title: Comprehensive Chemical Characterization of the Aerosol Emissions of a Vaping Product Based on a New Technology
Type: Publication
Author: James Nicol, Rory Fraser, Liam Walker, Chuan Liu, James Murphy, Christopher Proctor,
Description: Comprehensive Chemical Characterization of the Aerosol Emissions of a Vaping Product Based on a New Technology Chemical Research in Toxicology
Year: 2020
Tags: Vype, iSwitch, chemical characterization, Chemical Research in Toxicology, aerosol, vapour, vaping, vapour products, vape, coil and wick, distiller plate, technology,
Title: A cross-category puffing topography, mouth level exposure and consumption study among Italian users of tobacco and nicotine products
Type: Publication
Author: Joshua Jones, Sandra Slayford, Adam Gray, Kathryn Brick, Krishna Prasad, Christopher Proctor
Description: Scientific Reports
Year: 2020
Tags: cross-category puffing topography, topography, puffing, mouth level exposure, MLE, Italian, tobacco, nicotine, Italy, e-cigarette, electronic cigarettes, vapour, iSwitch, glo, THP, tobacco heating product,
Title: Genotoxicity evaluation of tobacco and nicotine delivery products: Part Two. In vitro micronucleus assay
Type: Publication
Author: Thorne, D.,Leverette, R.,Breheny, D.,Lloyd, M.,McEnaney, S.,Whitwell, J.,Clements, J.,Bombick, B.,Gaça, M.
Description: Food and Chemical Toxicology
Year: 2019
Tags: In vitro, tobacco heating product, THP, E-cigarette, vaping, vapour, IVMN, TPM, E-liquid, Nicotine equivalents, Food and Chemical Toxicology,
Title: An inter-laboratory in vitro assessment of cigarettes and next generation nicotine delivery products
Type: Publication
Author: M. Taylor,S. Ilto,S. Mori,D. Thorne,T. Nishino ,D. Breheny,M. Gaca,K. Yoshino,C. Proctor
Year: 2019
Tags: in vitro, vapour, e-cigarettes, tobacco heating products, THP, nicotine,
Title: Genotoxicity evaluation of tobacco and nicotine delivery products: Part One. Mouse lymphoma assay
Type: Publication
Author: Thorne, D.,Leverette, R.,Breheny, D.,Lloyd, M.,McEnaney, S.,Whitwell, J.,Clements, J.,Bombick, B.,Gaca, M.
Description: Food and Chemical Toxicology
Year: 2019
Tags: In vitro, NGP, THP, tobacco heating products, E-cigarette, MLA, TPM, E-liquid, Nicotine equivalents, Mouse lymphoma assay, vaping, vapour, Food and Chemical Toxicology
Title: Nicotine pharmacokinetics of electronic cigarettes: A review of the literature
Type: Publication
Author: Ian M.Fearon, Alison C.Eldridge, Nathan Gale, Mike McEwan, Mitchell F.Stiles, Elaine K.Round
Description: Regulatory Toxicology and Pharmacology
Year: 2018
Tags: Nicotine, electronic cigarettes, vapour products, vaping, BAT, Reynolds, RAI, A Better Tomorrow, pharmacokinetics, Ian Fearon, e-cigarette, clinical
Title: Characterisation of a vitrocell VC1 using nicotine dosimetry: An essential component toward standardised in vitro aerosol exposure of tobacco and next generation nicotine delivery products
Type: Publication
Author: Behrsing, H.,Aragon, M.,Adamson, J.,Sheehan, D.,Gaca, M.,Curren, R.,Hill, E.
Description: AIVT Volume 4, Number 2, 2018
Year: 2018
Tags: THP, Tobacco Heating Product, Heat-not-burn, AIVT
Title: Assessment of enamel discoloration in vitro following exposure to cigarette smoke and emissions from novel vapour and tobacco heating products
Type: Publication
Author: Dalrymple, A.,Badrock, T C.,Terry, A.,Barber, M.,Hall, P.,Thorne, D.,Gaca, M.,Coburn, S.,Proctor, C.
Description: American Journal of Dentistry
Year: 2018
Tags: THP, Tobacco Heating Product, Heat-not-burn, American Journal of Dentistry
Title: Extreme testing of undiluted e-cigarette aerosol in vitro using an Ames air-agar-interface technique
Type: Publication
Author: Thorne, D.,Hollings, M.,Seymour, A.,Adamson, J.,Dalrymple, A.,Ballantyne, M.,Gaca, M.
Description: Mutation Research
Year: 2018
Tags: RTP, Reduced Toxicant Prototype, Mutation Research
Title: A comparative assessment of e-cigarette aerosols and cigarette smoke on in vitro endothelial cell migration
Type: Publication
Author: Taylor, M.,Jaunky, T.,Hewitt, K.,Breheny, D.,Lowe, F.,Fearon, I.,Gaca, M.
Description: Toxicology Letters
Year: 2017
Tags: vaping, vapour, e-cigarettes, e-cig, smoke, Cardiovascular disease, CVD, Endothelial migration, Nicotine, in vitro, cell viability, cultured cells, Toxicology Letters
Title: Reduced biological effect of e-cigarette aerosol compared to cigarette smoke evaluated in vitro using normalized nicotine dose and RNA-seq-based toxicogenomics
Type: Publication
Author: Haswell, L.,Baxter, A.,Banerjee, A.,Verrastro, I.,Mushonganono, J.,Adamson, J.,Thorne, D.,Gaca, M.,Minet, E.
Description: Scientific Reports Scientific Reports
Year: 2017
Tags: vaping, vapour, e-cigarettes, e-cig, in vitro, aerosol, airway, exposure chamber, exposure, RNA, tissue, sequence, toxicogenomics, COPD, chronic obstructive pulmonary disease, gene, Scientific Reports
Title: A system dynamics modelling approach to assess the impact of launching a new nicotine product on population health outcomes
Type: Publication
Author: Hill, A.,Camacho, O.
Description: Regulatory Toxicology and Pharmacology
Year: 2017
Tags: vaping, vapour, e-cigarettes, e-cig, systems dynamics, model, modelling, modeling, Population studies, Nicotine, population health, Regulatory Toxicology and Pharmacology
Title: Nicotine quantification in vitro: A consistent dosimetry marker for e-cigarette aerosol and cigarette smoke generation
Type: Publication
Author: Adamson, J.,Li, X. ,Cui, H. ,Thorne, D.,Xie, F.,Gaca, M.
Description: Applied In Vitro Toxicology
Year: 2017
Tags: vaping, vapour, e-cigarettes, e-cig, nicotine, in vitro, dosimetry, aerosol, air-liquid interface, puffing, regime, Applied In Vitro Toxicology
Title: The comparative in vitro assessment of e-cigarette and cigarette smoke aerosols using the γH2AX assay and applied dose measurements
Type: Publication
Author: Thorne, D.,Larard, S.,Baxter, A.,Meredith, C.,Gaca, M.
Description: Toxicology Letters http://dx.doi.org/10.1016/j.toxlet.2016.12.006
Year: 2017
Tags: vaping, vapour, e-cigarettes, e-cig, in vitro, genotoxicity, aerosols, high content screening, HCS, exposure systems, air-liquid interface, Toxicology Letters
Title: E-cigarette Nicotine Delivery: Data and Learnings from Pharmacokinetic Studies
Type: Publication
Author: Fearon, I.,Eldridge, A.,Gale, N.,Shepperd, C. ,McEwan, M.,Camacho, O.,Nides, M.,McAdam, K.,Proctor, C.
Description: American Journal of Health Behavior
Year: 2016
Tags: e-cigarette, e-cig, vaping, vapour, nicotine, PK, pharmacokinetic, pharmacokinetics, PK, PK profiles, kinetics, clinical, plasma nicotine concentrations, American Journal of Health Behavior
Title: The mutagenic assessment of an electronic-cigarette and reference cigarette smoke using the Ames assay in strains TA98 and TA100
Type: Publication
Author: Thorne, D.,Crooks, I.,Hollings, M.,Seymour, A.,Meredith, C.,Gaca, M.
Description: Mutation Research/Genetic Toxicology and Environmental Mutagenesis
Year: 2016
Tags: e-cigarette, e-cig, vaping, vapour, aerosol, Ames, bacterial reverse mutation, mutagenicity, in vitro, WA, whole aerosol, TPM, total particulate matter, exposure, Mutation Research/Genetic Toxicology and Environmental Mutagenesis
Title: Development, validation and application of a device to measure e-cigarette users’ puffing topography
Type: Publication
Author: Cunningham, A.,Slayford, S.,Vas, C.,Gee, J. ,Costigan, S. ,Prasad, K.
Description: Scientific Reports
Year: 2016
Tags: puffing, topography, behaviour, MLE, mouth level exposure, dosimetry, exposure, emissions, regime, Scientific Reports
Title: Simulation of aerosol dynamics and deposition of combustible and electronic cigarette aerosols in the human respiratory tract
Type: Publication
Author: Pichelstorfer, L.,Hofmann, W.,Winkler-Heil, R.,Yurteri, C. U.,McAughey, J.
Description: Journal of Aerosol Science doi:10.1016/j.jaerosci.2016.01.017
Year: 2016
Tags: aerosols, dosimetry, deposition, lung, nicotine, vapour phase, particles, particle phase, modelling, model, modeling, combustibles, cigarettes, e-cig, e-cigarette, vaping, vapour, Journal of Aerosol Science
Title: A framework for the assessment of reduced-risk tobacco and nicotine products
Type: Publication
Author: Murphy, J.,Lowe, F.,Fearon, I.,Camacho, O.,Minet, E.
Description: Tobacco Science Research Conference (TSRC)
Year: 2015
Tags: A framework for the assessment of reduced-risk tobacco and nicotine products, Tobacco Science Research Conference (TSRC)
Title: Changes in biomarkers of exposure and biomarkers of potential harm after 360 days in smokers who either continue to smoke, switch to a tobacco heating product or quit smoking
Type: Publication
Author: Nathan Gale, Michael McEwan, George Hardie, Christopher J. Proctor & James Murphy
Description: Changes in biomarkers of exposure and biomarkers of potential harm after 360 days in smokers who either continue to smoke, switch to a tobacco heating product or quit smoking Internal and Emergency Medicine
Year: 2022
Tags: glo one-year clinical study, clinical study, glo clinical study, glo clinical, THP, tobacco heating products, heat not burn, heated tobacco, biomarkers of exposure, biomarkers of potential harm, glo 360, quit smoking, switch to tobacco heating product, A Better Tomorrow, Internal and Emergency Medicine, Nathan Gale, Michael McEwan, George Hardie, Christopher J. Proctor, James Murphy,
Title: Evaluation of behavioural, chemical, toxicological and clinical studies of a tobacco heated product glo™ and the potential for bridging from a foundational dataset to new product iterations
Type: Publication
Author: Sharon Goodall, Nathan Gale, David Thorne, Simone Hadley, Krishna Prasad, Ian Gilmour, Fabio Miazzi, Christopher Proctor
Description: Evaluation of behavioural, chemical, toxicological and clinical studies of a tobacco heated product glo™ and the potential for bridging from a foundational dataset to new product iterations Toxicology Reports
Year: 2022
Tags: bridging, glo, tobacco heating product, tobacco heated product, heat not burn, THP, new product, clinical studies, toxicological studies, chemical studies, behavioural studies, 9-step framework, risk assessment, Toxicology Reports, Science Direct, Sharon Goodall, Nathan Gale, David Thorne, Simone Hadley, Krishna Prasad, Ian Gilmour, Fabio Miazzi, Christopher Proctor,
Title: An Experimental Analytical and In Vitro Approach to Bridge Between Different Heated Tobacco Product Variants
Type: Publication
Author: Tomasz Jaunky, David Thorne, Andrew Baxter, Simone Hadley, Justin Frosina, Damien Breheny, James Murphy, Marianna Gaca,
Description: An Experimental Analytical and In Vitro Approach to Bridge Between Different Heated Tobacco Product Variants Sciendo
Year: 2022
Tags: Bridge, bridging, THP, glo tobacco heating products, heated tobacco, heat not burn, in vitro, product variants, Sciendo, Tomasz Jaunky, David Thorne, Andrew Baxter, Simone Hadley, Justin Frosina, Damien Breheny, James Murphy, Marianna Gaca, An Experimental Analytical and In Vitro Approach to Bridge Between Different Heated Tobacco Product Variants,
Title: A Laboratory Method to Measure Skin Surface Staining by Cigarette Smoke, Tobacco Heating Products and E-Cigarettes
Type: Publication
Author: Annette Dalrymple, Emma-Jayne Bean, Jesse Thissen, Holger Behrsing, Steven Coburn, James Murphy
Description: A Laboratory Method to Measure Skin Surface Staining by Cigarette Smoke, Tobacco Heating Products and E-Cigarettes Contributions to Tobacco Research
Year: 2022
Tags: Skin Surface Staining, staining, stained, skin, cigarettes, smoke, tobacco heating products, THP, glo, heat not burn, e-Cigarettes, vapour, vaping, Annette Dalrymple, Emma-Jayne Bean, Jesse Thissen, Holger Behrsing, Steven Coburn, James Murphy,
Title: Changes in biomarkers after 180 days of tobacco heating product use: a randomised trial
Type: Publication
Author: Nathan Gale, Michael McEwan, Oscar M. Camacho, George Hardie, Christopher J. Proctor, James Murphy
Description: Changes in biomarkers after 180 days of tobacco heating product use: a randomised trial Internal and Emergency Medicine
Year: 2021
Tags: Changes in biomarkers after 180 days of tobacco heating product use: a randomised trial, glo, glo clinical study, glo 180-day data, THP, heat not burn, alternatives to smoking, tobacco sticks, smoking, quitting smoking, A Better Tomorrow, David O'Reilly, biomarkers of exposure, biomarkers of potential harm, BAT, BAT Science, BAT research,
Title: A randomized controlled study in healthy participants to explore the exposure continuum when smokers switch to a tobacco heating product or an E-cigarette relative to cessation
Type: Publication
Author: McEwan M, Gale N, Ebajemito JK, Camacho OM, Hardie G, Proctor CJ, Murphy J.
Description: A randomized controlled study in healthy participants to explore the exposure continuum when smokers switch to a tobacco heating product or an E-cigarette relative to cessation Toxicology Reports
Year: 2021
Tags: A randomized controlled study in healthy participants to explore the exposure continuum when smokers switch to a tobacco heating product or an E-cigarette relative to cessation, vaping, vapour, vape, vaping vs smoking, quit smoking, THPs, heat not burn, glo, BAT, A Better Tomorrow, Mike McEwan,
Title: Modeling the Population Health Impacts of Heated Tobacco Products in Japan
Type: Publication
Author: Camacho OM et al
Description: Modeling the Population Health Impacts of Heated Tobacco Products in Japan Tobacco Regulatory Science
Year: 2021
Tags: Modeling the Population Health Impacts of Heated Tobacco Products in Japan, tobacco heating products, heat not burn, BAT, A Better Tomorrow, glo, THP, Japanese studies, Oscar Camacho,
Title: Cross-sectional Survey to Assess Tobacco and Nicotine Product Use since the Introduction of Tobacco Heating Products in Japan: Wave 1
Type: Publication
Author: Jones JD et al
Description: Cross-sectional Survey to Assess Tobacco and Nicotine Product Use since the Introduction of Tobacco Heating Products in Japan: Wave 1 Tobacco Regulatory Science
Year: 2021
Tags: Cross-sectional Survey to Assess Tobacco and Nicotine Product Use since the Introduction of Tobacco Heating Products in Japan: Wave 1, heat not burn, glo, THP, alternatives to smoking, Japanese studies, BAT, A Better Tomorrow, nicotine,
Title: The genotoxicological assessment of a tobacco heating product relative to cigarette smoke using the in vitro micronucleus assay
Type: Publication
Author: David Thorne, James Whitwell, Julie Clements, Paul Walker, Damien Breheny, Marianna Gaca,
Description: The genotoxicological assessment of a tobacco heating product relative to cigarette smoke using the in vitro micronucleus assay Toxicology Reports
Year: 2020
Tags: genotoxicological assessment, tobacco heating product, THP, glo, heat not burn, cigarette smoke, in vitro, micronucleus assay,
Title: Changes in Biomarkers of Exposure on Switching From a Conventional Cigarette to the glo Tobacco Heating Product: A Randomized, Controlled Ambulatory Study
Type: Publication
Author: Nathan Gale, Michael McEwan, Oscar M. Camacho, George Hardie, James Murphy, Christopher J Proctor,
Description: Changes in Biomarkers of Exposure on Switching From a Conventional Cigarette to the glo Tobacco Heating Product: A Randomized, Controlled Ambulatory Study Nicotine and Tobacco Research
Year: 2020
Tags: Biomarkers of Exposure, glo, Tobacco Heating Product, THP, Ambulatory Study, BoE, toxicants, clinical study, glo 12 month clinical study,
Title: Evaluation of a high-throughput in vitro endothelial cell migration assay for the assessment of nicotine and tobacco delivery products
Type: Publication
Author: Emma Bishop, Damien Breheny, Katherine Hewitt, Mark Taylor, Tomasz Jaunky, Oscar M. Camacho, David Thorne, Marianna Gaca,
Description: Evaluation of a high-throughput in vitro endothelial cell migration assay for the assessment of nicotine and tobacco delivery products Toxicology Letters
Year: 2020
Tags: in vitro, endothelial cell migration assay, nicotine, glo, tobacco heating product, THP, cytotoxicity, migration assay, scratch wound, scratch, wound, Endothelial cell migration, blood vessels, cardiovascular disease,
Title: Results from a 2018 cross-sectional survey in Tokyo, Osaka and Sendai to assess tobacco and nicotine product usage after the introduction of heated tobacco products (HTPs) in Japan
Type: Publication
Author: Jason Adamson, Claudia Kanitscheider, Krishna Prasad, Oscar M. Camacho, Elisabeth Beyerlein, Yoga Keralapura Bhagavan, Christopher Proctor, James Murphy,
Description: Harm Reduction Journal
Year: 2020
Tags: post-market surveillance, survey, cross-sectional survey, Tokyo, Osaka, Sendai, tobacco, nicotine, nicotine products, heated tobacco products, HTP, tobacco heating products, THP, Japan, glo,
Title: Statistical analysis plan for “A randomised, controlled study to evaluate the effects of switching from cigarette smoking to using a tobacco heating product on health effect indicators in healthy subjects”
Type: Publication
Author: Oscar M. Camacho, Andrew Hedge, Frazer Lowe, Nik Newland, Nathan Gale, Mike McEwan, and Christopher Proctor
Description: Statistical analysis plan for “A randomised, controlled study to evaluate the effects of switching from cigarette smoking to using a tobacco heating product on health effect indicators in healthy subjects” Contemporary Clinical Trials Communications
Year: 2020
Tags: tobacco heating products, THP, heat not burn, glo, cigarette, smoking, study, health effect indicators,
Title: Non-targeted analysis of the particulate phase of heated tobacco product aerosol and cigarette mainstream tobacco smoke by thermal desorption comprehensive two-dimensional gas chromatography with dual flame ionisation and mass spectrometric detection
Type: Publication
Author: B. Savareear,J. Escobar-Arnanz,M. Brokl,M. J. Saxton,C. Wright,C. Liu,JF. Focant
Description: Non-targeted analysis of the particulate phase of heated tobacco product aerosol and cigarette mainstream tobacco smoke by thermal desorption comprehensive two-dimensional gas chromatography with dual flame ionisation and mass spectrometric detection
Year: 2019
Tags: heated tobacco product, tobacco heating product, aerosol, cigarette, tobacco, smoke, gas chromatography, , Non-targeted analysis of the particulate phase of heated tobacco product aerosol and cigarette mainstream tobacco smoke by thermal desorption comprehensive two-dimensional gas chromatography with dual flame ionisation and mass spectrometric detection
Title: Protocol for a Japanese nationwide repeated cross-sectional study to assess tobacco and nicotine product use behaviour after market introduction of tobacco heating products (THPs)
Type: Publication
Author: Adamson, J.,Kanitscheider, C.,Prasad, K.,Camacho, O.M.,Beyerlein, E.,Keralapura, Y.,Proctor C.,Murphy, J.
Description: F1000 Research
Year: 2019
Tags: Post-market surveillance, Population studies, Cross sectional survey, Tobacco Heating Products, THPs, Harm reduction, glo, F1000 Research
Title: Thermo-oxidative degradation of aromatic flavour compounds under simulated tobacco heating product condition
Type: Publication
Author: Blazso, M.,Babinszki, B.,Czegeny Zs.,Barta-Rajnai, E.,Sebestyen, Z.,Jakab, E.,Nicol, J.,Liu, C.,McAdam, K.
Description: Journal of Analytical and Applied Pyrolysis
Year: 2018
Tags: THP, Tobacco Heating Product, Heat-not-burn, Journal of Analytical and Applied Pyrolysis, BAT, A Better Tomorrow, Chuan Liu
Title: Assessment of novel tobacco heating product THP1.0. Part 6: A comparative in vitro study using contemporary screening approaches
Type: Publication
Author: Mark Taylor, David Thorne, Tony Carr, Damien Breheny, Paul Walker, Christopher Proctor, Marianna Gaca,
Description: Assessment of novel tobacco heating product THP1.0. Part 6: A comparative in vitro study using contemporary screening approaches Regulatory Toxicology and Pharmacology
Year: 2018
Tags: tobacco heating product, THP, glo, in vitro, screening approaches, Regulatory Toxicology and Pharmacology,
Title: In vitro RNA-seq-based toxicogenomics assessment shows reduced biological effect of tobacco heating products when compared to cigarette smoke.
Type: Publication
Author: Haswell, L.,Corke, S.,Verrastro, I.,Baxter, A.,Banerjee, A.,Adamson, J.,Jaunky, T.,Proctor, C.,Gaca, M.,Minet E.
Description: Scientific Reports (SciReports)
Year: 2018
Tags: Vype, e-liquid, Vapour, E-cig, E-cigarette, Scientific Reports (SciReports)
Title: Assessment of tobacco heating product THP1.0. Part 8: Study to determine puffing topography, mouth level exposure and consumption among Japanese users
Type: Publication
Author: Jodie Gee, Krishna Prasad, Sandra Slayford, Adam Gray, Kathryn Nother, Anthony Cunningham, Eleni Mavropoulou, Christopher Proctor
Description: Assessment of tobacco heating product THP1.0. Part 8: Study to determine puffing topography, mouth level exposure and consumption among Japanese users Regulatory Toxicology and Pharmacology
Year: 2018
Tags: tobacco heating product, THP, glo, puffing topography, topography, mouth level exposure, MLE, Japanese, Japan,
Title: Assessment of tobacco heating product THP1.0. Part 2: Product design, operation and thermophysical characterisation
Type: Publication
Author: Eaton, D.,Blerta, J.,Forster, M.,Nicol, J.,Mavropoulou, E.,Scott, K.,Liu, C.,McAdam, K.,Murphy, J.,Proctor, C.
Description: Regulatory Toxicology and Pharmacology
Year: 2017
Tags: THP, tobacco heating product, heat-not-burn, glo, neostick, assessment framework, combustion, pyrolysis, aerosol, deposition, thermal degradation, heated, Regulatory Toxicology and Pharmacology
Title: Assessment of novel tobacco heating product THP1.0. Part 3: Comprehensive chemical characterisation of harmful and potentially harmful aerosol emissions
Type: Publication
Author: Forster, M.,Fiebelkorn, S.,Yuteri, C.,Mariner, D.,Liu, C.,Wright, C.,McAdam, K.,Murphy, J.,Proctor, C.
Description: Regulatory Toxicology and Pharmacology
Year: 2017
Tags: THP, tobacco heating product, heat-not-burn, glo, neostick, aerosol, emissions, heated, toxicants, analytical chemistry, Harm reduction, HPHCs, Harmful and Potentially Harmful Constituents, Regulatory Toxicology and Pharmacology
Title: Assessment of novel tobacco heating product THP1.0. Part 7: Comparative in vitro toxicological evaluation
Type: Publication
Author: Thorne, D.,Breheny, D.,Proctor, C.,Gaca, M.
Description: Regulatory Toxicology and Pharmacology
Year: 2017
Tags: THP, tobacco heating product, heat-not-burn, glo, neostick, in vitro, exposure, toxicants, CVD, cardiovascular disease, lung cancer, systems biology, cytotxicity, DNA, genotoxicity, mutagenicity, reduced risk, harm reduction, pre-clinical, Regulatory Toxicology and Pharmacology
Title: Assessment of tobacco heating product THP1.0. Part 9: The placement of a range of next-generation products on an emissions continuum relative to cigarettes via pre-clinical assessment studies
Type: Publication
Author: Murphy, J.,Liu, C.,McAdam, K.,Gaca, M.,Prasad, K.,Camacho, O.,McAughey, J.,Proctor, C.
Description: Regulatory Toxicology and Pharmacology
Year: 2017
Tags: THP, tobacco heating product, heat-not-burn, glo, neostick, emissions, risk continuum, harm reduction, assessment framework, pre-clinical, exposure, Regulatory Toxicology and Pharmacology
Title: Assessment of tobacco heating product THP1.0. Part 1: Series introduction
Type: Publication
Author: Proctor, C.
Description: Regulatory Toxicology and Pharmacology
Year: 2017
Tags: harm reduction, assessment framework, risk continuum, THP, tobacco heating product, heat-not-burn, glo, neostick, Regulatory Toxicology and Pharmacology
Title: Assessment of tobacco heating product THP1.0. Part 4: Characterisation of indoor air quality and odour
Type: Publication
Author: Forster, M.,McAughey, J.,Prasad, K.,Mavropoulou, E.,Proctor, C.
Description: Regulatory Toxicology and Pharmacology
Year: 2017
Tags: THP, tobacco heating product, heat-not-burn, glo, neostick, aerosol, emissions, heated, IAQ, indoor air quality, toxicants, analytical chemistry, Harm reduction, Regulatory Toxicology and Pharmacology
Title: Assessment of tobacco heating product THP1.0. Part 5: In vitro dosimetric and cytotoxic assessment
Type: Publication
Author: Jaunky, T.,Adamson, J.,Santopietro, S.,Terry, A.,Thorne, D.,Breheny, D.,Proctor, C.,Gaca, M.
Description: Regulatory Toxicology and Pharmacology
Year: 2017
Tags: THP, tobacco heating product, heat-not-burn, glo, neostick, in vitro, aerosol, dosimetry, exposure, exposure systems, air-liquid interface, cell culture, cytotoxicity, toxicology, Regulatory Toxicology and Pharmacology
Title: Headspace solid-phase microextraction coupled to comprehensive two-dimensional gas chromatography–time-of-flight mass spectrometry for the analysis of aerosol from tobacco heating product
Type: Publication
Author: Savareear, B.,Lizak, R.,Brokl, M.,Wright, C.,Liu, C.,Focant, J F.
Description: Journal of Chromotography A
Year: 2017
Tags: THP, tobacco heating product, heat-not-burn, glo, neostick, analytical chemistry, gas chromatography, mass spectrometry, toxicants, aerosol, particulate phase, Journal of Chromotography A
Title: Assessment of tobacco heating product THP 1.0. Part 8: Study to determine puffing topography, mouth level exposure and consumption among Japanese users
Type: Publication
Author: Gee, J.,Prasad, K.,Slayford, S.,Gray, A.,Brick, K.,Cunningham, A.,Mavropoulou, E.,Proctor, C.
Description: Regulatory Toxicology and Pharmacology
Year: 2017
Tags: THP, tobacco heating product, heat-not-burn, glo, neostick, puffing, mouth level exposure, MLE, topography, behaviour, consumer, puff duration, regime, Regulatory Toxicology and Pharmacology
Title: A randomised, controlled, two-centre open-label study in healthy Japanese subjects to evaluate the effect on biomarkers of exposure of switching from a conventional cigarette to a tobacco heating product
Type: Publication
Author: Gale, N.,McEwan, M.,Sherwood, N.,Eldridge, A.,Bowen, E.,McDermott, S.,Holmes, E.,Hedge, A.,Hossack, S.,Camacho, O.,Errington, G.,McAughey, J.,Murphy, J.,Liu, C.,Proctor, C.,Fearon, I.
Description: BMC Public Health
Year: 2017
Tags: THP, tobacco heating product, heat-not-burn, glo, neostick, clinical, Switching Study, toxicant exposure, emissions, Biomarkers of Exposure. BoE, Biomarkers of Biological Effect, BOBE, harm reduction, BMC Public Health
Title: A novel hybrid tobacco product that delivers a tobacco flavour note with vapour aerosol (part 1): Product operation and preliminary aerosol chemistry assessment
Type: Publication
Author: Poynton, S.,Sutton, J.,Goodall, S.,Margham, J.,Forster, M.,Scott, J.,Liu, C.,McAdam, K.,Murphy, J.,Proctor, C.
Description: Food and Chemical Toxicology
Year: 2017
Tags: iFuse, chemistry, aerosol, analytical chemistry, emissions, Harmful and Potentially Harmful Constituents, HPHCs, human airway, nicotine, characterisation, toxicants, puffing, Food and Chemical Toxicology, hybrid
Title: Thermal behaviour of selected flavour ingredients and additives under simulated cigarette combustion and tobacco heating conditions
Type: Publication
Description: Journal of Analytical and Applied Pyrolysis
Year: 2016
Tags: thp, tobacco heating product, heat-not-burn, themo, pyrolysis, gas chromatography, mass spectrometry, temperature, decompostion, degradation, Journal of Analytical and Applied Pyrolysis
Title: Assessment of biomarkers of exposure and potential harm, and physiological and subjective health measures in exclusive users of nicotine pouches and current, former and never smokers
Type: Publication
Author: David Azzopardi
Description: Assessment of biomarkers of exposure and potential harm, and physiological and subjective health measures in exclusive users of nicotine pouches and current, former and never smokers Biomarkers Journal
Year: 2022
Tags: Assessment of biomarkers of exposure and potential harm, and physiological and subjective health measures in exclusive users of nicotine pouches and current, former and never smokers, Velo, Velo pouches, nicotine, nicotine pouches, Velo nicotine, Velo cross-sectional study, clinical study, modern oral products, modern oral nicotine pouches, David Azzopardi, Biomarkers, Biomarkers Journal, BAT Science, A Better Tomorrow, BAT Velo study, smokeless,
Title: Chemical characterization of tobacco-free “modern” oral nicotine pouches and their position on the toxicant and risk continuums
Type: Publication
Author: Azzopardi D, Liu C, Murphy J
Description: Chemical characterization of tobacco-free “modern” oral nicotine pouches and their position on the toxicant and risk continuums Drug and Chemical Toxicology
Year: 2021
Tags: Chemical characterization of tobacco-free “modern” oral nicotine pouches and their position on the toxicant and risk continuums, MOPs, oral nicotine, nicotine pouches, white snus, harm reduction, tobacco harm reduction, smoking, BAT, A Better Tomorrow,
Title: A screening approach for the evaluation of tobacco-free ‘modern oral’ nicotine products using Real Time Cell Analysis
Type: Publication
Author: Nicole East, Emma Bishop, Damien Breheny, Marianna Gaca, David Thorne
Description: Toxicology Reports
Year: 2021
Tags: MOPs, Modern Oral Products, nicotine, tobacco-free, BAT, A Better Tomorrow, Nicole East, Real Time Cell Analysis, Toxicology Reports,
Title: An approach for the extract generation and toxicological assessment of tobacco-free ‘modern’ oral nicotine pouches
Type: Publication
Author: Bishop E, East N, Bozhilova S, Santopietro S, Smart D, Taylor M, Meredith S, Baxter A, Breheny D, Thorne D, Gaca M.
Description: Food and Chemical Toxicology
Year: 2020
Tags: Modern Oral Products, nicotine, nicotine pouches, Lyft Velo, snus, toxicology, toxicological assessment, tobacco-free, Emma Cheung, BAT, A Better Tomorrow,
Title: The composition of contemporary American and Swedish smokeless tobacco products
Type: Publication
Author: McAdam, K.G.,Kimpton, H.,Faizi, A.,Porter, A.,Rodu, B.
Description: BMC Chemistry
Year: 2019
Tags: The composition of contemporary American and Swedish smokeless tobacco products, BMC Chemistry
Title: Pathway-based predictive approaches for non-animal assessment of acute inhalation toxicity
Type: Publication
Author: Clippinger, A.J.,Allen, D.,Behrsing, H.,BéruBé, K.A.,Bolger, M.B.,Casey, W.,DeLorme, M.,Gaça, M.,Gehen, S.C.,Glover, K.,Hayden, P.,Hinderliter, P.,Hotchkiss, J.A.,Iskandar, A.,Keyser, B.,Luettich, K.,Ma-Hock, L.,Maionek, A.G.,Jarabeky, A.M.
Description: Toxicology in Vitro
Year: 2019
Tags: acute inhalation toxicity, in vitro, in silico, ex vivo, quantitative structure-activity relationships, QSAR, adverse outcome pathway, aggregate exposure pathway, dosimetry, integrated approach to testing and assessment, IATA, risk assessment, RAI, Reynolds, Toxicology in Vitro
Title: Ethyl carbamate in Swedish and American smokeless tobacco products and some factors affecting its concentration
Type: Publication
Author: McAdam, K.,Vas, C.,Kimpton, H.,Faizi, A.,Liu, C.,Porter, A.,Synnerdahl, T.,Karlsson, P.,Rodu, B.
Description: Chemistry Central Journal
Year: 2018
Tags: Ethyl carbamate in Swedish and American smokeless tobacco products and some factors affecting its concentration, Chemistry Central Journal
Title: Analysis of coumarin and angelica lactones in smokeless tobacco products
Type: Publication
Author: McAdam, K.,Enos, T.,Goss, C.,Kimpton, H.,Falzi, A.,Edwards, S.,Wright, C.,Porter, A.,Rodu, B.
Description: Chemistry Central Journal Chemistry Central Journal
Year: 2018
Tags: Coumarin, angelica, lactones, smokeless tobacco products, Chemistry Central Journal, Kevin McAdam
Title: Comprehensive survey of radionuclides in contemporary smokeless tobacco products
Type: Publication
Author: McAdam, K.,Kimpton, H.,Porter, A.,Liu C.,Faizi, A.,Mola, M.,McAughey, J.,Rodu, B.
Description: Chemistry Central Journal
Year: 2017
Tags: Comprehensive survey of radionuclides in contemporary smokeless tobacco products, Chemistry Central Journal
Title: Polycyclic aromatic hydrocarbons in US and Swedish smokeless tobacco products
Type: Publication
Author: McAdam, K.,Faizi, A.,Kimpton, H.,Porter, A.,Rodu, B.
Description: Chemistry Central Journal 7:151
Year: 2013
Tags: Smokeless tobacco, Snus, Polycyclic aromatic hydrocarbons, Chemistry Central Journal
Title: Combustible and non-combustible tobacco product preparations differentially regulate human peripheral blood mononuclear cell functions
Type: Publication
Author: Arimilli, S.,Damratoski, B.E.,Prasad, G.L.
Description: Toxicology in Vitro
Year: 2013
Tags: Tobacco product preparations, TPPs, T cells, NK cells, PBMCs, LPS, Cytotoxicity assay, combustibles, cigarettes, smokeless, snus, Toxicology in Vitro
Title: Multi-analyte approach for determining the extraction of tobacco constituents from pouched snus by consumers during use
Type: Publication
Author: Digard, H.,Gale, N.,Errington, G.,Peters, N.,McAdam, K.
Description: Chemistry Central Journal 7:55
Year: 2013
Tags: Snus, Dosimetry, Exposure assessment, Multi-analyte chemical analysis, Nicotine, Tobacco-specific nitrosamines, Chemistry Central Journal
Title: Determination of nicotine absorption from multiple tobacco products and nicotine gum
Type: Publication
Author: Digard, H.,Proctor, C.,Kulasekaran, A.,Malmqvist, U.,Richter, A.
Description: Nicotine and Tobacco Research 15(1):255-261
Year: 2013
Tags: Snus, smokeless tobacco, nicotine absorption, nicotine gum, Nicotine and Tobacco Research
Title: Should the health community promote smokeless tobacco (snus): Comments from British American Tobacco
Type: Publication
Author: Williamson, J.,Proctor, C.
Description: PLoS Medicine 4(10):1703-1705
Year: 2007
Tags: Health, smokeless tobacco, snus, harm reduction, PLoS Medicine
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