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In Vitro Testing Platform


The In Vitro Testing Industrial Platform (IVTIP) was established in December 1993. IVTIP is an organisation representing the interests of European chemical, pharmaceutical, cosmetics, tobacco and contract research companies with an active interest in in vitro testing for regulatory and safety assessment or in compound discovery and product development.

Currently there are over 30 member companies. IVTIP members are supportive of applying, where possible, the principle of the 3Rs: Replacement, Reduction and Refinement of animal testing in the field of in vitro testing. IVTIP has close interaction and dialogue with the European Commission (EC).

IVTIP members meet twice a year at meetings hosted by fellow members to discuss in vitro issues and follow developments in industrial as well as the EC, R&D programmes and projects with invited regulators, small and medium enterprises (SMEs) and academics. During the meetings state of the art presentations are given and position papers are drafted. The most recent meeting was held on 26th November 2009 was entitled, ‘Toxicology in the 21st Century - Working out way towards a visionary reality’, inspired by the latest US Environmental Protection Agency strategic plan for evaluating the toxicity of chemicals ‘Toxicity Testing in the 21st Century: A vision and a strategy.’ The meeting was hosted by one of the member companies, the Centre for Advanced Research and Development on Alternative Methods (CARDAM). The format of the meeting consisted of discussion sessions led by opinions and views presented by a number of distinguished speakers. The outcome of this meeting was a white paper and a topic for the Spring 2010 meeting, “Integrated In Vitro Testing Strategies- implementation challenges”.

British American Tobacco have been members of IVTIP since 2006 and currently is represented on the Board of Directors. In May 2008, we hosted the IVTIP Spring meeting in Southampton, UK which included a tour of our laboratories at the GR&D site. We fully support IVTIP's objectives to identify, develop and validate suitable in vitro alternatrives to limit the use of in vivo studies.

  1. Committee on toxicity testing and assessment of environmental agents, National Research Council. (2007). Toxicity testing in the 21st century: A vision and a strategy. The National Academies Press, Washington. 2007.ISBN-13: 978-0-309-10992-5.
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